| Event Start Date: 7. October 2026 | Event End Date: 7. October 2026 | Event Venue: Online: Zoom |
Date and time: October 7th, 2026, 18:00-19:30 (6:00-7:30 pm Oslo time).
We are pleased to announce an upcoming online lecture by Dr. Daniel Freeman from MIT Lincoln Laboratory.
Title: Experiential Brain Mapping with Transcranial Focused Ultrasound
Bio
Daniel Freeman is a scientist at MIT Lincoln Laboratory whose research spans neurotechnology, device physics, and analog computing. His current work includes the use of transcranial focused ultrasound to investigate the neural basis of subjective experience, analog computing approaches for energy-efficient AI, MEMS hydrophones, quantum magnetometers, and electronic textiles. He received his PhD in biomedical engineering from Boston University and completed postdoctoral fellowships at Harvard Medical School and MIT.
Abstract
Identifying the brain structures that contribute directly to subjective experience remains one of the most challenging problems in science. While much insight has been gained by measuring brain activity in humans with EEG and fMRI, the field would benefit greatly from new methods of non-invasive brain stimulation. Transcranial focused ultrasound (tFUS) offers a new approach that enables millimeter-scale spatial precision across both cortical and deep brain structures. Here, we discuss how tFUS can be combined with psychophysics and EEG measurements to help localize the neural substrate of subjective experience. Specifically, causal perturbation may help distinguish neural activity that generates experience from activity involved in unconscious processing, including processes involved in cognition and behavioral report. Activity evoked by tFUS will inevitably propagate through interconnected neural circuits, complicating the ability to distinguish correlation from causation. We discuss how combining tFUS stimulation with temporally resolved neural measurements may address this challenge.
References
- Daniel K. Freeman, Brian Odegaard, Seung-Schik Yoo, Matthias Michel (2026) Transcranial focused ultrasound for identifying the neural substrate of conscious perception. Neuroscience and Biobehavioral Reviews 180 (2026) 106485
- Pellow C, Pichardo S, Pike GB. A systematic review of preclinical and clinical transcranial ultrasound neuromodulation and opportunities for functional connectomics. Brain Stimul. 2024 Jul-Aug;17(4):734-751.
- Aubry JF, Attali D, Schafer ME, Fouragnan E, Caskey CF, Chen R, Darmani G, Bubrick EJ, Sallet J, Butler CR, Stagg CJ, Klein-Flügge MC, Yoo SS, Holland CK, Treeby B, Martin E, Verhagen L, Butts Pauly K. ITRUSST consensus on biophysical safety for transcranial ultrasound stimulation. Brain Stimul. 2025 Nov-Dec;18(6):1896-1905.
- D. K. Freeman and S. J. Byrnes, “Optimal Frequency for Wireless Power Transmission Into the Body: Efficiency Versus Received Power,” in IEEE Transactions on Antennas and Propagation, vol. 67, no. 6, pp. 4073-4083, June 2019.
- Freeman DK, Rizzo JF 3rd, Fried SI. Encoding visual information in retinal ganglion cells with prosthetic stimulation. J Neural Eng. 2011 Jun;8(3):035005.
- Freeman DK, Rizzo JF 3rd, Fried SI. Encoding visual information in retinal ganglion cells with prosthetic stimulation. J Neural Eng. 2011 Jun;8(3):035005. doi: 10.1088/1741-2560/8/3/035005. Epub 2011 May 18. PMID: 21593546; PMCID: PMC3157751.

